While intuitively, it would seem that if someone gets enough calories, and those calories contain enough of any given vitamin or nutrient, it would be impossible for them to experience deficiencies in that vitamin or nutrient and by extension the detrimental health effects of such a deficiency.
But in some intriguing new Cornell University findings, this seeming truism is overturned. Geri Clark, writing for the Cornell Chronicle, states in his article, Obesity leads to ‘silent’ vitamin A deficiency in organs, that: “The new findings suggest that obesity in humans is also associated with low vitamin A levels in many organs. Such deficiencies would have corresponding health effects.” How is it possible that two sets of mice (normal weight and obese), fed the same diet with sufficient vitamin A levels, would have such disparate levels of the vitamin in their organs? Researchers don’t have all the answers yet, but for more insights see Geri Clark’s quoted article here and the original Cornell Study here.